2016, Volume 10, Issue 1
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RekordInteraction of three-drug combination of lacosamide, carbamazepine and phenobarbital in the mouse maximal electroshock-induced seizure model – an isobolographic analysis / Interakcja trójlekowej kombinacji lakozamidu, karbamazepiny i fenobarbitalu w teście maksymalnego wstrząsu elektrycznego u myszy - analiza izobolograficzna(Państwowa Szkoła Wyższa im. Papieża Jana Pawła II w Białej Podlaskiej, 2016-04-07)Background. Epilepsy is one of the serious neurological diseases characterized by seizures that affect about 1% of people worldwide (65 million), and therefore, epilepsy can be considered as a disease of civilization. Although seizures are controllable with antiepileptic drugs (AEDs) in about 70% of cases, it remains still about 30% of epilepsy patients inadequately medicated with these AEDs, who need a full control of their seizure attacks. One of the treatment options in these patients is application of two or three AEDs in combination. The aim of this study was to characterize the anticonvulsant effects of a combination of three AEDs (i.e., carbamazepine [CBZ], lacosamide [LCM] and phenobarbital [PB]) at the fixed-ratio of 1:1:1 in the mouse maximal electroshock (MES)-induced seizure model. Materials and methods. Tonic hind limb extension (seizure activity) was evoked in adult male albino Swiss mice by a current (sine-wave, 25 mA, 500 V, 50 Hz, 0.2 s stimulus duration) delivered via auricular electrodes. Type Iisobolographic analysis was used to analyze the three-drug combination. Results. Type I isobolographic analysis revealed that the combination of CBZ, LCM and PB (at the fixed-ratio of 1:1:1) exerted additive interaction with a slight tendency towards antagonism in the mouse MES-induced seizure model. Conclusions. A special caution is advised to patients taking LCM in combination with CBZ and PB because this three-drug combination offered additive interaction with a slight tendency towards antagonism in the mouse MES model.
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RekordThe role of school sexual education in health promotion / Rola szkolnej edukacji seksualnej w promocji zdrowia(Państwowa Szkoła Wyższa im. Papieża Jana Pawła II w Białej Podlaskiej, 2016-04-07)Sexuality is an integral part of personality of each human being. No earnestly conducted sex education is a common cause of engaging in risky sexual behaviours.The aim of the study is to evaluate the role of sex education in health promotion and to present the results of the studies of the effects of school sex education on sexual behaviour of young people.The period of adolescence is characterized by a more frequent risk-taking behaviour. Among adolescents it is observed that the average age of sexual initiation has decreased, the frequency of making sexual contact and a number of sexual partners has increased, as well as the insufficient dissemination of the use of condoms and other methods of contraception every time sexual intercourse takes place.The task of health promotion is to influence determinants of health, among others, through sex education. Research confirms the positive impact of complex sex education, carried out in accordance with the recommendations of international organizations, on a lower frequency of engaging in risky sexual behaviour. It seems appropriate to take action to disseminate appropriate for the level of psychosexual development sex education in schools.
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RekordThe review of results of research on breastfeeding considering medicinal and prophylactic aspects / Przegląd wyników badań na temat karmienia piersią kobiet z uwzględnieniem aspektów leczniczych i profilaktycznych(Państwowa Szkoła Wyższa im. Papieża Jana Pawła II w Białej Podlaskiej, 2016-04-07)Breastfeeding is an irreplaceable, in biological and emotional aspect, basis of mother and child’s health. The aim of this paper was to present the review of research results on advantages of natural feeding and benefits of breastfeeding, presentation of breast massage technique as a way of supporting natural feeding, as well as contraindications to breastfeeding. In spite of the propagation, the number of mothers who feed their children in natural way is still considerably low. At present, the American Academy of Paediatrics recommends nursing for 6 months, and continuing it until first year of child’s life (or longer, depending on mother or child’s needs), introducing, at the same time, supplementary food. The issue of breastfeeding should be widely spread among women mainly by midwifes, who should propagate nursing with commitment and provide proper information, emphasising its positive influence on the health of mother and child.
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RekordSubjective health profiles among Ukrainian students of Medical Vocational School / Subiektywne profile zdrowia wśród ukraińskiej młodzieży szkolnej Studium Medycznego(Państwowa Szkoła Wyższa im. Papieża Jana Pawła II w Białej Podlaskiej, 2016-04-07)Background. Understanding various dimensions of health is a key factor to properly identify health risks. The purpose of the research is to acquire knowledge concerning positive health and survival skills by the Ukrainian students of Medical Vocational School in Lutsk. Material and methods. The study group comprised 467 female students aged 15-25 years old who were the attendants of Postsecondary Vocational School in Lutsk on: Pharmacy, Medicine, Obstetrics, Nursing and Laboratory Diagnostics specialties. A subjective questionnaire was used, which focused on: somatic, mental and social health profiles together with survival skills. Results. The results indicated the intensification of individual profiles, with the highest value of social health. Somatic health identified HR as its highest index, for mental health it was tolerance and for social health- respecting basic values. When it comes to the survival skill health profile tolerating body imbalance obtained the highest index. Conclusions. Most of the specialties showed a domination of different health profiles, which allowed to demonstrate forms of self-reported health models from the specialties of Nursing and Medicine.
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RekordDiversity of physical activity among the school youth depending on the type of place of residence / Zróżnicowanie aktywności fizycznej młodzieży szkolnej w zależności od rodzaju miejsca zamieszkania(Państwowa Szkoła Wyższa im. Papieża Jana Pawła II w Białej Podlaskiej, 2016-04-07)Background. The objective of the study was to reveal diversity of physical activity among the school youth depending on the type of place of residence (single-family house, block of flats). Material and methods. The research conducted in 2015 covered 646 students from junior high schools and post-gymnasium schools in Biała Podlaska with an average age of 18,8 ± 0,84 years. The method of research which was applied was the International Physical Activity Questionnaire (IPAQ) within its full form. Conclusions. It was indicated that the school youth, including in particular boys residing in family houses show higher level of physical activity than their peers living in blocks of flats.