2025, Volume 19, Issue 2

Stały URI dla tej kolekcji

https://hdl.handle.net/20.500.13044/2218

Przeglądaj

Przeglądanie 2025, Volume 19, Issue 2 według Tytuł

  • Rekord
    Analysis of musculoskeletal injuries among adult Internet gaming players: a cross-sectional study
    (Akademia Bialska im. Jana Pawła II, 2025-02-20) Cieśla, Artur ; Kochman, Maciej ; Vašková, Monika ; Guzik, Agnieszka ; Czarny, Wojciech ; Pelc, Kamil ; Ružbarska, Beata ; Drużbicki, Mariusz
    Background. I nternet g aming ( IG) l eads t o s ocial d isturbances, b ehavioral d isorders, and physical impairments. The cross-sectional study focused on back pain experienced by IG players and investigated the relationships between pain complaints and the factors potentially predicting. Material and methods. The survey was conducted online and a total of 1,104 IG players were recruited for the study. Disability assessment was performed using The Oswestry Disability Index (ODI). Results. The majority of the respondents (72.1%) reported they experienced back pain. Assessment of pain showed significant differences (p<0.0001) with greater pain levels in the lumbar spine. The findings also show significant differences (p<0.001) in disability level between respondents who reported they did and did not get regular sleep at night. Significant differences (p<0.001) were also shown in the disability levels between the respondents engaging in sports or exercise and those who did not do any sport or exercise. Conclusions. The prevalence of back pain complaints in IG players was high. Higher disability levels were observed in older gamers, individuals with lumbar spine pain, and those who did not get regular sleep at night, or do any sport or exercise. Future prospective longitudinal studies investigating the cause-and-effect nature of the findings are necessary.
  • Rekord
    APOE as a risk factor for Alzheimer’s disease and lipid metabolism disorders: molecular analysis
    (Akademia Bialska im. Jana Pawła II, 2024-05-08) Kowalska, Ewa ; Madej, Łukasz ; Szafraniec, Kacper ; Rachuna, Jarosław
    The gene encoding apolipoprotein E (APOE) plays a key role in many biological processes, including lipid metabolism, brain homeostasis, and functioning of the circulatory system. APOE gene polymorphism is one of the most important risk factors in the context of Alzheimer’s disease (AD), which is the most common cause of dementia. Different variants of APOE alleles, particularly APOE ε4, are associated with an increased risk of AD and accelerated progression of this disease. Mechanisms by which APOE ε4 contributes to AD pathogenesis include amyloid metabolism disorders, tautopenias, immune system dysfunction, and functional abnormalities of the blood-brain barrier. The APOE gene may play an important role not only in the pathogenesis of AD, but also in the development of cardiovascular diseases, such as coronary heart disease, stroke and atherosclerosis. As in AD, different variants of APOE alleles may affect lipid metabolism, inflammation, vascular functions and the processes of apoptosis, which translates into an increased risk of diseases. The article presents the current state of knowledge about the role and importance of the APOE gene in the pathomechanism of AD and cardiovascular diseases. Understanding molecular mechanisms and gene-environment interactions associated with APOE may contribute to changes in the diagnostic process. The development and improvement of genetic tests may help in early detection and treatment of diseases, and even, in some cases, prevent their occurrence.
  • Rekord
    Assessing the impact of home-based conventional exercise and cryotherapy on lower limb muscle strength and walking ability in individuals with knee osteoarthritis: a randomized controlled clinical trial
    (Akademia Bialska im. Jana Pawła II, 2024-05-17) MohammedSadiq, Hawar Abdulrazaq ; Rasool, Mohammad Tahir
    Background. K nee osteoarthritis ( KOA) i s a c ommon a ge-related joint c ondition c ausing discomfort, reduced physical capability, functional diminishment, and diminished life quality. Material and methods. I n t his c linical r andomized c ontrolled t rial, K OA-diagnosed individuals were randomly allocated into three cohorts: an experimental cohort (n=17), a control cohort (n=14), and a secondary control cohort (n=17). Interventions included two months of home-based exercise (HBE) with cryotherapy, exclusive HBE engagement for two months, and routine therapeutic and physiotherapeutic interventions at a medical facility. Results. The experimental and first control cohorts exhibited notably enhanced lower-limb muscle strength and walking capabilities compared with the second control cohort after two months. Both experimental and first control groups showed significantly lower fivetime sit-to-stand scores (5TSTS) and walking 40 meters scores compared with the second control group (p<0.0001). However, the control group displayed slightly improved scores in 5TSTS and 4x10-meter walking relative to the experimental group, though not statistically significant. Conclusions. Combining HBE with cryotherapy did not significantly improve lower-limb muscle strength and walking in KOA patients.
  • Rekord
    Bariatric surgery: a modern method reducing the risk of cancer development
    (Akademia Bialska im. Jana Pawła II, 2024-05-23) Jerzak, Aneta ; Jakubowska, Katarzyna ; Janocha, Aleksandra ; Ziemba, Paweł
    Recently, we have encountered a fascinating article written by Davey et al. [1] that investigated the potential colorectal cancer prevention effects of bariatric surgery. We consider this topic to be extremely important to both individuals with obesity and doctors, because more frequent qualifications for bariatric surgery will not only contribute to weight loss but also reduce the risk of cancer development.
  • Rekord
    Barriers and facilitators for early and exclusive breastfeeding in the Duhok Governorate in Iraqi Kurdistan
    (Akademia Bialska im. Jana Pawła II, 2024-04-18) Haleem, Khaled Hussein ; Mohammed, Bashar Ibrahim ; Abdulrahman, Nareen Arif ; Haleem, Azad Abduljabar ; Atrushi, Akrem Mohammad
    Background. Breast milk is the best f ood satisfying a baby’s needs. Sociodemographic factors, antenatal care practices, and professional assistance at birth may be barriers against this. The aim of the study was to estimate the prevalence of exclusivity and to identify the barriers to breastfeeding. Material and methods. A cross-sectional study was conducted from August 2022-2023 involving 336 mothers of infants (6-24 months) who visited primary healthcare centers. Information on socioeconomic background, pregnancy and delivery details, and awareness of breastfeeding benefits was collected using a pretested questionnaire. Data analysis was performed and a p-value ≤ 0.05 was considered significant. Results. The whole number of infants breastfed was 146 (43.45%), and for six months, this was 25 (7.4%). The significant factors were: living in Duhok City, not having sufficient knowledge about the breastfeeding, decision to breastfeed during pregnancy, starting breastfeeding soon after delivery, vaginal delivery, order of birth, not giving sugar after delivery, being supported by the husband, holding the baby after delivery, knowledge of benefits of breastfeeding. The most significant factors associated with exclusive breastfeeding were maternal age <25 years, diseases during pregnancy, birth order (2nd o r 3rd ), explanation of the benefits of breastfeeding by health professionals, decision to exclusively breastfeed during pregnancy, delivery in a governmental hospital, and holding the baby after birth (OR=1.09, 1.037, 1.048, 1.677, 5.869, 1.097, and 2.45, respectively). Conclusions. This study identified multifaceted barriers to early exclusive breastfeeding in the Duhok Governorate.
  • Rekord
    Effect of obesity on the relationship between glycosylated hemoglobin and insulin resistance in young adults
    (Akademia Bialska im. Jana Pawła II, 2024-05-17) Topal, Sümeyra ; Yalnızoğlu Çaka, Sinem ; Çınar, Nursan ; Altınkaynak, Sevin
    Background. The purpose of this prospective case-control research was to compare insulin resistance in obese and non-obese students with regard to glycosylated hemoglobin (HbA1c) and the homeostatic model assessment insulin resistance (HOMA-IR). Material and methods. This study was conducted with a total of 122 students who were determined to be obese (n=35), overweight (n=43) and normal weight (n=44), among students at a university in Türkiye (n=891). Students were first classified according to their Body Mass Index (BMI) and blood samples were taken for fasting blood glucose, HgA1c, and insulin levels. Results. Of the 891 students participating in the study, 4.83% (n=43) were overweight and 3.93% (n=35) were obese. HbA1c levels were found below 5.7 for 72.7% of normal weight students and HbA1c levels were found between 5.7-6.4 for 65.7% of obese students. There was a significant statistical difference between them (p=0.001). When the HOMA-IR value was >3.16, there was a significant difference between the obese group and the other groups (p=0.042). There was a significant positive correlation between BMI and both HbA1c (r=0.299, p=0.001) and HOMA-IR (r=0.432, p=0.000). Conclusions. It was found that HOMA-IR was more common in obese students, and early diagnosis of insulin resistance might be HbA1c. HbA1c can be used since it is inexpensive and simple to evaluate insulin resistance in obese young adults.
  • Rekord
    Investigation of GST and drug resistance protein expressions in relation to chemotherapy in breast cancer
    (Akademia Bialska im. Jana Pawła II, 2024-05-08) Kaya Kocdogan, Arzu ; Kilic, Murat ; Oguztuzun, Serpil ; Benzer, Emine ; Dilek, Gulay ; Kahraman, Yavuz Selim ; Gulcelik, Mehmet Ali
    Background. During cancer therapy, resistance to chemotherapeutic agents is common and often linked to multidrug resistance mechanisms. Glutathione S-transferases (GSTs) and ATP-binding cassette (ABC) transporters, including multidrug resistance (MDR) proteins, multidrug resistance-associated proteins (MRPs), and breast cancer resistance protein (BCRP), are implicated in drug resistance. Material and methods. Protein expressions were determined in the tumor and surrounding tumor free breast tissues of 145 breast cancer patients by immunohistochemistry technique. Among 145 patients, 50 received preoperative (neoadjuvant) chemotherapy, and 95 received postoperative (adjuvant) chemotherapy. Results. In 50 neoadjuvant breast cancer patients, GSTA1, GSTK1, GSTM1, GSTO1, GSTP1, GSTS1, GSTT1, GSTZ1, MDR1, MRP1, MRP2, MRP3, MRP7, and BCRP expressions were higher in tumor epithelium compared to normal epithelium (p<0.05). In 95 adjuvant breast cancer patients, GSTA1, GSTK1, GSTM1, GSTP1, GSTT1, GSTZ1, MDR1, MRP1, MRP2, and MRP3 expressions were higher in tumor epithelium than in normal epithelium (p<0.05). GSTP1, GSTT1, and MRP3 expressions were significantly higher in neoadjuvant compared to adjuvant-treated breast cancer patients’ tumor tissues (p<0.05). Conclusions. GSTP1, GSTT1, and MRP3 may be important in inactivating the chemotherapeutic agents used in platinum-based treatment and are thus responsible for the drug resistance in breast cancer patients.
  • Rekord
    Participation of firefighters in interventions to mental disorders as support to medical teams: a review of the literature
    (Akademia Bialska im. Jana Pawła II, 2025-04-01) Maczulski, Krzysztof ; Dudziński, Łukasz ; Jaśkiewicz, Filip ; Czyżewski, Łukasz
    Fire service role in supporting medical teams during emergency interventions requiring specialized equipment or additional staff support is important. The purpose of the narrative review is to analyze how firefighting units collaborate with medical teams during interventions related to mental and behavioral disorders. The review also considers the psychological challenges faced by firefighters as a result of repeated exposure to stress. A narrative literature review has been conducted by using resources available in PubMed, Google Scholar and ResearchGate databases, covering publications from 2020-2024. The inclusion criteria were peer-reviewed articles, guidelines, recommendations and expert papers pertinent to the topic under analysis. The material selection process was based upon the PRISMA protocol. Twelve publications, divided into two groups, were included in the review, viz.: studies on the psychological effects of chronic stress in firefighters and analyses of joint interventions by firefighters and medical teams in cases of behavioral disorders. The results indicate an important role of firefighters in providing technical support. Cooperation between firefighters and medical teams plays a key role in an effective management of interventions in case of mental and behavioral disorders.
  • Rekord
    Pentalogy of Cantrell: a case report
    (Akademia Bialska im. Jana Pawła II, 2024-05-17) Płusajska, Justyna ; Świercz, Grzegorz ; Młodawski, Jakub ; Malmur, Mariusz ; Zalega, Magdalena
    Cantrell’s pentalogy is a rare developmental disorder occurring between the 14th and 18th day of embryonic life. Diagnosis is possible in the first trimester, when the rupturing of the continuity of the anterior chest cavity and abdominal walls is usually found. Ectopic heart and umbilical hernia is also characteristic. In this article, a case of a thirty-three-year-old patient in second pregnancy was described, who was diagnosed with developmental disorders during a routine visit to a gynecologist. Woman was referred to the Laboratory of Prenatal Research, where the fetus was diagnosed with: umbilical cord hernia, diaphragmatic hernia with diaphragmatic defect, sternal defect, ectopic heart and pericardial defect, the swelling of the entire fetus – NT 5 mm – and the reverse flow in the DV were visualized. The woman and the child’s father, after having been presented with the prognosis, decided to terminate the pregnancy. Due to the heterogeneous picture of disorders occurring in pentalogy of Cantrell and the small number of cases described in the literature, each case should be approached with caution and in an individual manner. Abnormalities in the structure of the heart additionally compounded by coexisting disorders are crucial for the prognosis and they determine the method and order of treatment.
  • Rekord
    Physical activity and the quality of life in the physical dimension of respondents from Independent Culture Centers in Poland
    (Akademia Bialska im. Jana Pawła II, 2025-02-25) Bergier, Michał
    Background. The aim of the study was to investigate the potential relationship between physical activity and quality of life of people representing Independent Culture Centers (ICC). It is probably the first scientific article addressing the issue of people from such a niche group as ICC members and examining their physical activity and quality of life. Material and methods. The study group consisted of 104 people (38 women and 66 men), aged 19 to 46, members of ICC located in Poland. The level of physical activity of the respondents was examined using the International Physical Activity Questionnaire (IPAQ). The quality of life in the physical dimension was assessed using the 36-Short Form Health Survey questionnaire (SF36v2). Results. Even though in each of the analyzed levels of physical activity intensity differences were demonstrated between respondents from the compared groups of people with different levels of quality of life, in none of the analyzed cases was a statistically significant differentiation demonstrated. Conclusions. The results obtained by the research ICC respondents are unusual in light of previous research related to the issue under consideration. Therefore, further research is needed among ICC members, which would help indicate what a relationship is there between physical activity and quality of life.
  • Rekord
    Synergistic impact of exercise and GLP-1 receptor agonist treatment: addressing metabolic syndrome, abdominal obesity, and inflammation
    (Akademia Bialska im. Jana Pawła II, 2024-05-17) Kuśmierski, Jakub ; Kuśmierska, Martyna
    We are eager to share the findings from a recent article that we had the pleasure of reading, which we believe holds profound significance. Authored by Sandsdal et al. [1], this randomized controlled clinical trial delves into the impact of a combination of exercise and GLP-1 receptor agonist treatment on the severity of metabolic syndrome, abdominal obesity, and inflammation.
  • Rekord
    Validation of the Multiple Sclerosis Quality of Life Questionnaire-54 in Slovakia
    (Akademia Bialska im. Jana Pawła II, 2024-05-17) Majerníková, Ľudmila ; Obročníková, Andrea ; Hudáková, Anna ; Grešš Halász, Beata
    Background. Quality of life assessment of patients with multiple sclerosis (MS) is not commonly performed in the Slovak Republic due to the unavailability of a validated Slovak version of a specific assessment tool. Material and methods. The aim of this study was to transculturally adapt and validate the Slovak version of the Multiple Sclerosis Quality of Life Questionnaire (MSQoL-54). Psychometric analysis was performed by assessing reliability (Cronbach α), internal validation and external validation by measuring correlation with clinical factors such Expanded Disability Status Scale (EDSS) as well as other demographic factors. The questionnaire was validated on a sample of 298 patients with MS. Results. Based on the results of the factor analysis, it can be concluded that the Slovak version of the MSQoL-54 questionnaire has comparable psychometric properties to the original version. External validation using EDSS showed a statistically significant inverse (negative) correlation on all components of the questionnaire. Conclusions. The Slovak version of the MSQoL-54 questionnaire assessment tool can be used by Slovak healthcare professionals for a more comprehensive treatment of patients with MS.