(Państwowa Szkoła Wyższa im. Papieża Jana Pawła II w Białej Podlaskiej, 2017-07-28)
Krzemień, Paweł Jan
Diagnosing Lyme borreliosis, despite years of standardization, continues to encounter
difficulties. They result primarily from the lack of a good marker of active infection and one
helpful in assessing the effectiveness of the treatment. So far, a certain diagnosis of Lyme
borreliosis can be made only in a patient with erythema migrans (EM). Unfortunately, this
symptom occurs only in some patients. According to the recommendations of the Polish
Society of Epidemiologists and Doctors of Infectious Diseases, the effectiveness of treatment
is determined by the disappearance of clinical symptoms. For this reason, for years, we have
been looking for highly sensitive and diagnostically specific laboratory markers. These
would allow for rapid identification of fresh infections with Borrelia spirochetes as well
as simple monitoring of treatment efficacy. According to many of the recently published
publications, the solution to the second of the presented problems may be the measurement
of IgG antibodies to the surface antigen of Borrelia burgdorferi s.l. VlsE / C6.