(Akademia Bialska im. Jana Pawła II, 2024-04-09)
Kuśmierska, Martyna; Kuśmierski, Jakub; Ujma, Przemysław
The worldwide incidence of obesity, affecting roughly 2 billion individuals, is
a major health issue attributed to inactive lifestyles and poor eating habits. It is
a leading risk factor for metabolic diseases.
In healthy adults, the gut microbiome is predominantly made up of Firmicutes and
Bacteroidetes, which represent approximately 70% of the entire microbial population.
Other groups such as Proteobacteria, Verrucomicrobia, Actinobacteria, Fusobacteria,
and Cyanobacteria also exist but in lesser quantities. When comparing the gut
flora of obese individuals to those with a lean body type, there’s a notable increase in
Firmicutes and a decrease in Bacteroidetes among the obese.
In the meta-analysis conducted by Chanda D et al. the composition of the gut
microbiome in obese individuals was analyzed, revealing a consistent reduction in
diversity compared to their lean counterparts.